Rat GRO/KC or Growth-Regulated Protein alpha, also known as C-X-C Motif Chemokine 1 and Platelet-Derived Growth Factor-Inducible Protein KC, is a 96 amino acid cytokine encoded by the Cxcl1 gene located at locus 14p22 on chromosome 14. After initial synthesis of the peptide, the 24 residue signal sequence is cleaved, allowing the 72 residue GRO/KC protein to fold properly. GRO/KC, an intercrine alpha (chemokine CxC) family member, essentially has chemotactic activity for neutrophils and contributes to neutrophil activation during inflammation.
Intended Use: Rat GRO/KC ELISA is specifically designed for the accurate quantitation of Rat GRO/KC from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive. This Rat GRO/KC is for research use only. Not for diagnostic or therapeutic procedures.
The kit uses a sandwich ELISA format to quantify the target cytokine between two layers of antibodies (i.e. capture and detection antibody). The cytokine to be measured contains at least two antigenic epitope capable of binding to antibody, since at least two antibodies act in the sandwich. The advantage of Sandwich ELISA is that the sample does not have to be purified before analysis, and the assay can be very sensitive upto pg/ml levels (more sensitive than direct or indirect ELISA). A highly efficient blocking and stabilizing proprietary solution is used in the kit. All KRISHGEN cytokine ELISA kits are optimized to give the best possible noise:signal ratios.
KRISHGEN BIOSYSTEMS is a leading manufacturer of immunoassay kits including ELISA. KRISHGEN has over 200 publications and citations to its credit which speaks of its quality and accuracy. Leaders in many areas of research, ELISAs manufactured by KRISHGEN are used for quality research and reproducibility at competitive prices. Diverse product range includes ELISA for diagnostics, cytokines, biopharmaceuticals, HCP, downstream contamination, PK studies for Mabs, immunogenicity, vaccine, animal health testing, plant pathology, GMO and food safety.
ELISA 96 wells
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