Interleukin-6 (IL-6) is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis and may play a central role in host defense mechanisms. The abnormal production of IL-6 was first suggested to be related to polyclonal B-cell activation with autoantibody production in patients with cardiac myxoma. Since then, IL-6 has been suggested to be involved in the pathogenesis of a variety of diseases.
Intended Use: Rat IL-6 ELISA is specifically designed for the accurate quantitation of Rat IL-6 from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive. This Rat IL-6 is for research use only. Not for diagnostic or therapeutic procedures.
The kit uses a sandwich ELISA format to quantify the target cytokine between two layers of antibodies (i.e. capture and detection antibody). The cytokine to be measured contains at least two antigenic epitope capable of binding to antibody, since at least two antibodies act in the sandwich. The advantage of Sandwich ELISA is that the sample does not have to be purified before analysis, and the assay can be very sensitive upto pg/ml levels (more sensitive than direct or indirect ELISA). A highly efficient blocking and stabilizing proprietary solution is used in the kit. All KRISHGEN cytokine ELISA kits are optimized to give the best possible noise:signal ratios.
KRISHGEN BIOSYSTEMS is a leading manufacturer of immunoassay kits including ELISA. KRISHGEN has over 200 publications and citations to its credit which speaks of its quality and accuracy. Leaders in many areas of research, ELISAs manufactured by KRISHGEN are used for quality research and reproducibility at competitive prices. Diverse product range includes ELISA for diagnostics, cytokines, biopharmaceuticals, HCP, downstream contamination, PK studies for Mabs, immunogenicity, vaccine, animal health testing, plant pathology, GMO and food safety.
ELISA 96 wells
Activity profile of methanolic extract of Ficus bengalensis: Comparison with some clinically effective drugs
Biomedicine & Aging Pathology 2014
Atul T. Thite, Rajesh R. Patil, Suresh Ramnath Naik Corresponding author contact information, E-mail the corresponding author
Silymarin liposomes improves oral bioavailability of silybin besides target- ing hepatocytes, and immune cells
Pharmacological Reports 2014
Nitesh Kumara, Amita Raib, Neetinkumar D. Reddya, P. Vasanth Raja, 1, Prateek Jaina, Praful Deshpandea, Geetha Mathewa, N. Gopalan Kuttya, Nayanabhirama Udupaa, C. Mallikarjuna Rao.
Spermidine ameliorates 3-nitropropionic acid (3-NP)-induced striatal toxicity: Possible role of oxidative stress, neuroinflammation, and neurotransmitters
Physiology and Behavior 2015
Sumit Jamwala, Puneet Kumara
Oleic Acid Induced Acute Lung Injury/Acute Respiratory Distress Syndrome Animal Model
Research Journal of Pharmacy and Technology 2014
Hagawane Tejashree N.1, Mahuvakar Aashish M., Gaikwad Rajiv V., Kshirsagar Nilima A.
Lack of Detectable Allergenicity in Genetically Modified Maize Containing “Cry” Proteins as Compared to Native Maize Based on In Silico & In Vitro Analysis
PLOS One 2015
Chandni Mathur, Pooran C. Kathuria, Pushpa Dahiya, Anand B. Singh
Ameliorative effects of Tricholepis glaberrima in experimentally induced hepatic damage in rats: Modulation of cytokines functions
Journal of Ethnopharmacology 2015
Shilpa S Gound, Vishnu N. Thakare, Sharjil Khan, Raju R. Wadekar, Suresh R. Naik
Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats
Singh S., Kumar P.
Beneficial effect of rice bran extract against 3-nitropropionic acid induced experimental Huntington's disease in rats
Navneet Kaur, Sumit Jamwal, Rahul Deshmukh, Vinod Gauttam, Puneet Kumar
Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory Mechanism
Neurotoxicity Research 2015
Sumit Jamwal, Shamsher Singh, Navneet Kaur, Puneet Kumar
L-theanine, a Component of Green Tea Prevents 3-Nitropropionic Acid (3-NP)-Induced Striatal Toxicity by Modulating Nitric Oxide Pathway
Molecular Neurobiology 2016
Sumit Jamwal, Puneet Kumar
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