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Introduction:
Tumor necrosis factor-alpha (TNF-Alpha), a homotrimeric 17 kDa protein, is a potent mediator of inflammatory and metabolic functions. TNF-Alpha was originally detected as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Further, TNF-Alpha has been implied as central mediator in shock induced by gram negative micro-organisms. The cytokine TNF functions as a central mediator in many inflammatory and immunological processes. It can be induced by various products of microorganisms and by various cytokines but it also induces on its turn the production of many cytokines. Signal transduction occurs via two types of TNF-receptors, the p55 and p75 TNF-receptors. The receptors differ strongly in their intracellular signaling pathways.
Intended Use:
Rat TNF-Alpha ELISA is specifically designed for the accurate quantitation of Rat TNF-Alpha from cell culture supernatant,serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.
ELISA Features include:
– Ready to use protocol
– Standardisation and High Reproducibility
– Lot to Lot Consistency
– Accuracy and Precision
Validated against seven points for a Gold Ring Standard Quality ELISA – the benchmark sign for Krishgen quality.
The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be serum, plasma, biological fluids and cell culture supernatant.
If you have published a paper by using any of our ELISA since 01/01/2023, kindly fill out the “Krishgen Publication Reward Application Form” with complete information and send it by at email: info@krishgen.com, with the subject “Krishgen Publication Reward”. We will get back to you with the Amazon / Krishgen Credit Reward after we confirm it ASAP!