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SARS-CoV-2 Surrogate Virus Neutralization Test (sVNT) ELISA

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ELISA 1 x 96 wells

Enzyme Immunoassay for qualitative and quantitative detection all types of

 neutralizating antibodies against SARS-CoV-2 in human serum or plasma. CE IVD.


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This Surrogate Virus Neutralization Test / SARS-CoV-2 Virus Neutralising Antibodies ELISA is the WORLD's ONLY CE IVD MARKED sVNT TEST commercially available. 

Enzyme Immunoassay for qualitative and quantitative detection all types of neutralization antibodies against SARS-CoV-2 in human serum or plasma.

The kit employs a blocking ELISA technique which mimics the virus neutralization process. SARS-CoV-2-neutralizing antibodies primarily target the trimeric spike (S) glycoproteins on the viral surface that mediate entry into host cells. The S protein has two functional subunits that mediate cell attachment (the S1 subunit, existing of four core domains S1A through S1D) and fusion of the viral and cellular membrane (the S2 subunit). Potent neutralizing antibodies often target the receptor interaction site in S1, disabling receptor interactions.

The spike proteins of SARS-CoV-2 commonly bind to the human angiotensin converting enzyme 2 (ACE2) protein as a host receptor through their S1B domain. Receptor interaction is known to trigger irreversible conformational changes in coronavirus spike proteins enabling membrane fusion. SARS-CoV-2 initiates an immune response, which leads to the production of antibodies. These neutralizing antibodies provide protection against future infection from SARS-CoV-2, as they remain in the circulatory system for months to years post infection.

This ELISA is ready to use and CE IVD.

The major advantage of sVNT is that it can be rapidly conducted in most research or clinical laboratories without the need to use live biological materials and biosafety containment.
Suppliers Krishgen Biosystems
Other Specifications Sample Type: Serum, Plasma. Detection: Qualitative
Reactivity or Species Human SARS-CoV-2
Sensitivity uses cutoff with Positive and Negative Control
Calibrator Range Qualitative / Quantitative
Storage Condition 2 - 8 Deg C
Usage CE IVD / RUO
ELISA Type Sandwich

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