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ATMP/GENE THERAPY


ADVANCE THERAPY MEDICINAL PRODUCTS | CELLULAR AND GENE THERAPY PRODUCTS | REAGENTS


KRISHGEN is a leading global supplier of high quality reagents and tools in the expanding market of cell and gene therapy and regenerative medicine.

The company was founded in 2003 and is headquartered in Mumbai, India. KRISHGEN has more than 15 years of expertise in offering the development and GMP manufacturing of cell and gene therapy products.

As a trusted supplier, KRISHGEN offers a comprehensive product portfolio to ensure a seamless transition from research to commercialization. Included in our product portfolio are recombinant human cytokines, serum-free media and closed cell culture systems. Our products combine a maximum of quality and safety with excellent performance due to state-of- the-art production, stringent in-house quality control and comprehensive documentation. All these factors help to simplify qualification and validation for your market authorization.

Apart from our in-house expertise, we rely on specialized leading companies and institutes across the world to offer you a one-shop solution for your needs. Backed by qualified scientists and researchers with years of experience, we understand you. This helps us give a customized tailor-fit product and service.

Dendritic Cells
DCs represent unique antigen-producing cells capable of sensitizing T cells to antigens. They play a central role in the regulation of innate and adaptive immunity. DC therapy represents a new and promising immunotherapeutic approach for treatment of different types of cancer.

rh Cytokines
Genlisa™ GM-CSF, IL-4, IL-1beta, TNFalpha, IL-6, IL-10, IFNgamma
(GMP/preclinical grade)

Medium
Krishgen™ GMP DC

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC050

Genlisa™ GM-CSF

500 ug / 1000 ug

KRC086

Genlisa™ IL-4

500 ug / 1000 ug

KRC074

Genlisa™ IL-1beta

500 ug / 1000 ug

KRC410

Genlisa™ TNFalpha

500 ug / 1000 ug

KRC090

Genlisa™ IL-6

500 ug / 1000 ug

KRC101

Genlisa™ IL-10

500 ug / 1000 ug

KRC071

Genlisa™ IFNgamma

500 ug / 1000 ug

Medium

KMM01

Krishgen™ GMP DC

500 ml

 

 

 

Embryonic Stem Cells & Induced Pluripotent Stem Cells
ES and iPS cells can differentiate into all cell types of the human body and have the capacity to self-renew. Potential therapeutic applications include basic research, drug testing and regenerative medicine. ES and iPS cells are in addition used as new cell sources for the generation of DC and T cell therapies.

rh Cytokines
Genlisa™ EGF, FGF-2, Activin A, OSM, HGF, TGF-beta1
(GMP/preclinical grade)

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC031

Genlisa™ EGF

500 ug / 1000 ug

KRC044

Genlisa™ FGF-2

500 ug / 1000 ug

KRC009

Genlisa™ Activin A

500 ug / 1000 ug

KRC210

Genlisa™ OSM

500 ug / 1000 ug

KRC063

Genlisa™ HGF

500 ug / 1000 ug

KRC401

Genlisa™ TGF-beta1

500 ug / 1000 ug

Hematopoietic Stem and Progenitor Cells
HSCs are widely used for transplantation after high- dose chemotherapy of lymphoma, leukemia and certain immune-deficiency illnesses.

rh Cytokines
Genlisa™ SCF, TPO, Flt-3L, IL-3, IL-6
(GMP/preclinical grade)

Medium
Krishgen™ GMP SCGM

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC328

Genlisa™ SCF

500 ug / 1000 ug

KRC417

Genlisa™ TPO

500 ug / 1000 ug

KRC047

Genlisa™ Flt-3L

500 ug / 1000 ug

KRC082

Genlisa™ IL-3

500 ug / 1000 ug

KRC090

Genlisa™ IL-6

500 ug / 1000 ug

Medium

KMM02

Krishgen™ GMP SCGM

500 ml

T Cells
T cells play a central role in cell-mediated immunity. T cell immunotherapy for cancer, chronic infection and autoimmunity is a rapidly growing field with very promising results in clinical trials. There are currently four types of therapies: chimeric antigen receptor (CAR), tumor-infiltrating lymphocytes (TILs), regulatory T cells (Treg) and T cell receptor (TCR) engineered T cells.

rh Cytokines
Genlisa™ IL-2, IL-7, IL-10, IL-15, IL-21, TGF-beta1
(GMP/preclinical grade)

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC078

Genlisa™ IL-2

500 ug / 1000 ug

KRC096

Genlisa™ IL-7

500 ug / 1000 ug

KRC101

Genlisa™ IL-10

500 ug / 1000 ug

KRC118

Genlisa™ IL-15

500 ug / 1000 ug

KRC121

Genlisa™ IL-21

500 ug / 1000 ug

KRC401

Genlisa™ TGF-beta1

500 ug / 1000 ug

Natural Killer Cells
NK cells are a subset of cytotoxic lymphocytes involved in the innate immune system. They play a major role in the host-rejection of both tumor and virally infected cells. Immunotherapy, based on NK cell infusion, is a potential adjuvant treatment for many cancers.

rh Cytokines
Genlisa™ IL-2, IL-15, IL-21
(GMP/preclinical grade)

Medium
Krishgen™ GMP SCGM

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC078

Genlisa™ IL-2

500 ug / 1000 ug

KRC118

Genlisa™ IL-15

500 ug / 1000 ug

KRC121

Genlisa™ IL-21

500 ug / 1000 ug

Medium

KMM02

Krishgen™ GMP SCGM

500 ml

Mesenchymal Stem Cells
MSCs are multipotent stem cells that can be differentiated into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, pancreatic islets cells and neuronal cells. They hold great therapeutic promise in the field of cell-based tissue engineering and regenerative medicine. MSCs are being used for the prevention or treatment of GvHD after allogeneic blood stem cell transplantation. Their immunomodulatory properties are furthermore employed in autoimmune diseases such as diabetes and Crohn’s disease.

rh Cytokines
Genlisa™ EGF, FGF-2, PDGF-BB, TGF-beta1
(GMP/preclinical grade)

Medium
Krishgen™ MSC, preclinical grade

Cells
Krishgen™ hUC-MSC

Coating Material
Krishgen™ Gelatin, preclinical grade

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC031

Genlisa™ EGF

500 ug / 1000 ug

KRC044

Genlisa™ FGF-2

500 ug / 1000 ug

KRC223

Genlisa™ PDGF-BB

500 ug / 1000 ug

KRC401

Genlisa™ TGF-beta1

500 ug / 1000 ug

Medium

KMM03

Krishgen™ MSC, preclinical grade

500 ml

Cells

KCC01

Krishgen™ hUC-MSC

1 million cells / vial

Coating Material

KCS01

Krishgen™ Gelatin, preclinical grade

1 gm

Chondrocytes
Chondrocytes are the only cell type resident in the cartilage. Chondrocytes are, for example, used for the generation of articular cartilage injuries in the knee (Autologous Chondrocyte Transplantation, ACT).

rh Cytokines
Genlisa™ FGF-2, PDGF-BB
(GMP/preclinical grade)

Coating Material
Krishgen™ Gelatin, preclinical grade

Cat No

Product Particulars

Pack Size

rh Cytokines

KRC044

Genlisa™ FGF-2

500 ug / 1000 ug

KRC223

Genlisa™ PDGF-BB

500 ug / 1000 ug

Coating Material

KCS01

Krishgen™ Gelatin, preclinical grade

1 gm

(CAR-T) CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY
(TCR) T-CELL RECEPTOR THERAPY


 

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