KRISHGEN is a leading global supplier
of high quality reagents and tools in the expanding market of cell and gene
therapy and regenerative medicine.
The company was founded in 2003
and is headquartered in Mumbai, India. KRISHGEN has more than 15 years of
expertise in offering the development and GMP manufacturing of cell and gene
As a trusted supplier, KRISHGEN
offers a comprehensive product portfolio to ensure a seamless transition from
research to commercialization. Included in our product portfolio are
recombinant human cytokines, serum-free media and closed cell culture systems.
Our products combine a maximum of quality and safety with excellent performance
due to state-of- the-art production, stringent in-house quality control and
comprehensive documentation. All these factors help to simplify qualification
and validation for your market authorization.
Apart from our in-house
expertise, we rely on specialized leading companies and institutes across the
world to offer you a one-shop solution for your needs. Backed by qualified
scientists and researchers with years of experience, we understand you. This
helps us give a customized tailor-fit product and service.
DCs represent unique antigen-producing cells capable of sensitizing T cells to
antigens. They play a central role in the regulation of innate and adaptive
immunity. DC therapy represents a new and promising immunotherapeutic approach
for treatment of different types of cancer.
Embryonic Stem Cells &
Induced Pluripotent Stem Cells
ES and iPS cells can differentiate into all cell types of the human body and
have the capacity to self-renew. Potential therapeutic applications include
basic research, drug testing and regenerative medicine. ES and iPS cells are in
addition used as new cell sources for the generation of DC and T cell
T cells play a central role in cell-mediated immunity. T cell immunotherapy for
cancer, chronic infection and autoimmunity is a rapidly growing field with very
promising results in clinical trials. There are currently four types of
therapies: chimeric antigen receptor (CAR), tumor-infiltrating lymphocytes
(TILs), regulatory T cells (Treg) and T cell receptor (TCR) engineered T cells.
Natural Killer Cells
NK cells are a subset of cytotoxic lymphocytes involved in the innate immune
system. They play a major role in the host-rejection of both tumor and virally
infected cells. Immunotherapy, based on NK cell infusion, is a potential
adjuvant treatment for many cancers.
Mesenchymal Stem Cells
MSCs are multipotent stem cells that can be differentiated into a variety of
cell types, including osteoblasts, chondrocytes, myocytes, adipocytes,
pancreatic islets cells and neuronal cells. They hold great therapeutic promise
in the field of cell-based tissue engineering and regenerative medicine. MSCs
are being used for the prevention or treatment of GvHD after allogeneic blood
stem cell transplantation. Their immunomodulatory properties are furthermore
employed in autoimmune diseases such as diabetes and Crohn’s disease.
Krishgen™ Gelatin, preclinical grade
ug / 1000 ug
ug / 1000 ug
ug / 1000 ug
ug / 1000 ug
MSC, preclinical grade
million cells / vial
Gelatin, preclinical grade
Chondrocytes are the only cell type resident in the cartilage. Chondrocytes
are, for example, used for the generation of articular cartilage injuries in
the knee (Autologous Chondrocyte Transplantation, ACT).
Dr Jayaraman D. Lead Scientist, leading CRO company
I have been working with a team from KRISHGEN on an assay development and customization before giving us. The project was complicated and needed technical expertise in immunology as we were working on an insulin analog. I was very pleased with their technical competence and also mastering immunology and delivering a tough project to us on time. Their rigor, punctuality and expertise have been a recipe for the high standards, I would expect for such project from them. Kudos, Krishgen Team!!!
Mr Ramesh Sravanan, VP-Supply Chain
The expertise and command on the logistics chain including the regulatory
guidelines from Krishgen is something we admire. As they often indicate, let us
do the supplies, and let your team focus on science … is really something the
company works on. Delivering consistently, with less than 1% error or delay
consistently is the key to their success.
Dr Keith Stevens, visiting Scientist, Norfolk University, UK
To have a company understand science and work with them, is a pleasure. Krishgen
not only sells but understands what it sells in terms of the complex cutting
Mellisa Karlowski, Lead Researcher, east coast US CRO
The company is good on understanding its customers, is transparent and
speaks science. This makes it easier for us to work with them.